Clinical Eponyms
E-F

 

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This list is available for the Palm Pilot at Andrew Yee's website.

Eale’s disease
 Isolated, peripheral retinal vasculitis
Ebstein’s anomaly
 Malformation characterized by the downward displacement of the tricuspid valve into the right ventricle due to anomalous attachment of the tricuspid leaflets; associated with maternal exposure to Li
Edinger-Westphal nucleus
 Part of CN III - impacts the curvature of the lens and the diameter of the pupil
Edwards’s syndrome
 Trisomy 18, mental retardation, prominent occiput, micrognathia, low-set ears, rocker-bottom feet, flexion deformities of the fingers, and congenital heart disease
Eisenmenger complex
 A ventricular septal defect with right ventricular hypertrophy, severe pulmonary hypertension, and frequent straddling of the defect by a misplaced aortic root
Eisenmenger syndrome
 Cardiac failure with significant right to left shunt producing cyanosis due to higher pressure on the right side of the shunt; usually due to the Eisenmenger complex any anomalous circulatory communication that leads to obliterative pulmonary vascular disease; or maybe
Ellsworth-Howard test
 For diagnosis of pseudohypoparathyroidism, can administer PTH
Elschnig spots
 Yellow (early) or hyperpigmented (late) patches of retinal pigment epithelium overlying infarcted choriocapillaris lobules in hypertensive retinopathy
Emery Dreifus muscular dystrophy
 Proximal weakness with quite pronounced muscle contractions and by severe cardiac arrhythmias which may cause sudden death
Epsom salts
 Magnesium sulfate, laxative
Epstein’s pearls
 Small, white cysts along the median raphe of the hard palate
Epstein-Barr virus
 EBV binds to CD21 found on epithelial cells and B cells; however a large number of T suppressor cells and EBV specific cells are seen as atypical lymphocytes
Erb palsy
 C5 and C6 nerve roots
Erlenmeyer’s flask deformity
 Seen in osteopetrosis, where the ends of long bones are bulbous
erythroplasia of Queyrat
 Carcinoma in situ of the glans penis Auguste Queyrat, French dermatologist, born 1872
Evan’s syndrome
 ITP and immunohemolytic anemia
Ewart’s sign
 In large pericardial effusion, dullness to percussion of the left lung over the angle of the scapula may occur; due to compressive atelectasis by the large pericardial sac
Ewing’s sarcoma
 Onion skinning

 

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facies Hippocratica
 The mask of death following peritonitis, i.e. as a result of vomiting and depressed circulation, the face becomes pinched and anxious, the cheeks hollow, and the eyes dim and beringed with dark circles
factor V Leiden
 Arg(506) Alpha Gln, results in resistance to cleavage by activated protein C (an anticoagulant), found in 20% of patients with venous thromboembolism, 6% of US population
Fallot, tetralogy of
 1. ventricular septal defect; 2. infundibular, valvar, or supravalvar pulmonic stenosis; 3. an anteriorly displaced aorta that receives blood from both ventricles; 4. right ventricular hypertrophy
Fanconi’s anemia
 Autosomal recessive, predisposal to aplastic anemia, progressive bone failure at age 5-7, congenital malformations
Fanconi’s anemia
 Autosomal recessive, predisposal to aplastic anemia, progressive bone failure at age 5-7, congenital malformations (frequently defects in thumbs or forearms, kidneys, GI, skin); 20% develop cancer (primarily AML but also in skin, GI, GU); diagnosed by seeing increased sensitivity of FA cells to bifunctional alkylating agents (e.g. diepoxybutane or mitomycin C)
farmer’s skin
 Cutis rhomboidalis nuchae
Felty’s syndrome
 The combined features of rheumatoid arthritis, splenomegaly, and neutropenia, and leg ulcers; associated with HLA-DR;
Ferguson’s reflex
 Anesthesia in OB, interruption of oxytocin release in response to cervical dilatation may cause uterine inhibition
fifth disease
 Erythema infectiosum, associated with parvovirus B19 infection, characterized by "slapped cheeks" and erythematous lacy eruption on the trunk and extremities; other 4 childhood rash diseases: measles, rubella, scarlet fever, and roseola (herpesvirus VI)
Fisher’s syndrome
 Ataxia with ophthalmoplegia and areflexia; a form of polyneuroradiculitis
Fitz-Hugh-Curtis syndrome
 Associated with spread of gonococci or chlamydiae: perihepatitis manifested by right upper quadrant or bilateral upper abdominal pain and tenderness and occasionally by a hepatic friction rib
Flatbush diabetes
 GAD antibody negative NIDDM in adult black subjects with diabetic ketoacidosis and increased frequency of human leukocyte antigen DR3 and DR4
Folstein
 Standardized "mini mental-status exam" - a 30 question questionnaire designed to assist in the diagnosis of dementia
foramen of Magendie
 Midline foramen exiting out of fourth ventricle
foramen of Winslow
 Anterior portal triad; posterior IVC and right crus of diaphragm; superior caudate lobe; inferior superior part of duodenum, portal triad
foramina of Luschka
 Two laterally placed foramens exiting out of fourth ventricle
foramina of Monro
 Connects each of the lateral ventricles with the third ventricle
Forrester classification
 In myocardial infarction, I, PWP<18 and CI>2.2 L/min/m2, 2% mort; II, PWP>18 and CI>2.2, 10% mort; III, CI<2.2 and PWP<18, 12% mort; IV, PWP>18 and CI<2.2, 54% mort
Foster Kennedy syndrome
 Optic atrophy, contralateral papilledema, and anosmia; may be associated with olfactory groove meningioma
Fothergill’s sign
 In rectus sheath hematomas, tender mass that does not cross the midline and remains palpable when patient tenses the rectus muscle (bluish discoloration not usually seen until 3 or 4 days)
Fournier’s gangrene
 Necrotizing infection of the perineal and genital fascia
Fouville’s syndrome
 Dorsal pontine injury giving rise to lateral gaze palsy, ipsilateral facial palsy, contralateral hemiparesis
Fox's sign
 In hemorrhagic pancreatitis, ecchymosis of the inguinal ligament due to blood tracking from the retroperitoneum and collecting at the inguinal ligament
Franklin’s disease
 Gamma heavy chain disease, characterized by LAD, fever, anemia, malaise, HSM, and weakness, most distinctive symptom palatal edema
Freidreich’s foot
 Seen in Freidreich's ataxia, pes cavus with hammer toe
Frey syndrome
 Gustatory sweating or auriculotemporal syndrome seen in the context of parotid surgery; ipsilateral forehead becoming drenched with sweat apparently because of some salivery nerve fibers connecting with autonomic efferents
Friedreich’s ataxia
 A spinocerebellar degeneration, AR manifesting at 11 years, a less common AD 20 years; initial symptoms, gait ataxia, hand clumsiness, dysarthria, DTRs absent (extensor plantar present), joint position and vibratory sense impaired, sometimes loss of pain and temperature, paralyzed over course of 20 years, high incidence of diabetes and hypertrophic cardiomyopathy (dilated less common) and arrhythmias
Friedreich’s sign
 Exaggerated y descent in patients with increased venous pressure, associated with an S3; also associated with constrictive pericarditis
Froment’s sign
 Dx of ulnar nerve lesion; caused by flexor pollicus longus (median nerve) which comes into action when the patient attempts to grip a flat object between the thumb and the hand, and causes flexion at the interphalangeal joint

 

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From Andrew Yee, Harvard Med '00