Clinical Eponyms
I-J

 

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This list is available for the Palm Pilot at Andrew Yee's website.

Imerslund-Grösbeck syndrome
An autosomal recessive condition where transport inward of cobalamin from ileal receptors is faulty; associated with megaloblastic anemia, proteinuria, renal tubular defects, and various congenital abnormalities of the renal pelvis and ureter
Irish’s node
Left axillary adenopathy associated with metastatic disease, e.g. gastric CA
Isaacs’s syndrome
Neuromyotonia; continuous muscle stiffness, rippling muscle movements (myokymia), delayed relaxation following muscle contraction believed to be due to autoantibodies to presynaptic potassium channels
Ishihara plates
Pseudoisochromatic plates (plates with color dots for numbers) for testing color vision
Ito cells
Vitamin A fat-storage cells, of mesenchymal origin found in the space of Disse; during development of cirrhosis, they become activated, transform into fibroblast-like cells

 

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Jaccoud’s arthritis
In SLE, ulnar deviation of the fingers, swan neck deformities, and subluxations, initially reversible but can become fixed
Jackson-Weiss syndrome
Craniosynostoses as well as limb defects, mutations if FGFR2, broad great toes
Janeway lesions
In infective endocarditis; nonpainful, small, erythematous or hemorrhagic macules or nodules of palms or soles; more common in acute bacterial endocarditis but occur in subacute bacterial endocarditis
Jansen metaphyseal chondrodysplasia
An autosomal dominant form of dwarfism resulting from an activating mutation in the PTHrP receptor, premature ossification from acceleration of the transition from proliferative to hypertrophic chondrocytes
Jarisch-Herxheimer reaction
Sudden fevers, rigors, and persistent hypotension following antimicrobial treatment of louse-borne relapsing fever (Borrelia recurrentis (spirochete) infection) or syphilis; treatment with anti-TNF-alpha Fab before penicillin suppresses this reaction (NEJM 335:311)
Jendrassik maneuver
Subject grips hands and pulls apart to facilitate lower extremity reflex testing
Jod-Basedow phenomenon
Thyroid hyperfunction induced by excess iodine ingestion in patients with various thyroid disorders; Jod German for iodine; K. A. Von Basedow
Joffroy sign
In thyrotoxicosis, absence of forehead wrinkling with upward gaze, the head being tilted down; disorder of the arithmetic faculty in the early stages of organic brain disease
Jolly test
Good test for distinguishing between Lambert-Eton syndrome and myasthenia gravis. Friedrich Jolly, German neurologist, 1844-1904
Jones’s fracture
Fracture at the base of the fifth metatarsal diaphysis

 

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From Andrew Yee, Harvard Med '00