Clinical Eponyms
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This list is available for the Palm Pilot at Andrew Yee's website.

Uhthoff’s phenomenon
 In multiple sclerosis, sensitivity of symptoms to changes in body temperature or exercise (e.g., visual loss with exercise); initial description in 1890 amblyopia following exercise
unhappy triad
 Lateral knee injury resulting in ACL tear, MCL tear, and medial meniscal injury
Unterberger’s stepping test
 For assessing vestibular function, having patient step in one spot with the eye closed; in peripheral lesions, body rotates to side of lesion whereas in central disorders, deviation is irregular
van den Bergh reaction
 Used to distinguish between unconjugated and conjugated bilirubin; bilirubin pigments are exposed to sulfanilic acid to generate diazo conjugates, forming chromogenic products
van der Woude syndrome
 An AD condition in which lip pits are seen in all gene carriers but only some individuals have cleft lips with or without cleft palate owing to variable expressivity
van Wyk-Grumbach syndrome
 Primary hypothyroidism associated with precocious puberty and galactorrhea
van’t Hoff’s law
 For calculating osmotic pressure
Vincent’s infection
 Acute necrotizing ulcerative gingivitis, occurring in patients with decreased resistance to infection, from concurrent infection with the symbiotic bacteria Fusobacterium fusiforme and Borrelia vincentii
Virchow’s node
 Supraclavicular adenopathy associated with a malignancy, often on left side, associated with stomach cancer among other neoplasms
Virchow’s triad
 Predisposing factors in thrombus formation 1. endothelial injury, 2. hypercoagulability 3. stasis or turbulence of blood flow; first described in 1860
Virchow-Robin spaces
 Perivascular spaces in brain; become unusually widened in edema of the brain
Vogt-Koyanagi-Harada syndrome
 Bilateral, diffuse granulomatous uveitis associated with poliosis (premature grayoing of some or all of the hair), vitiligo, alopecia, and central nervous system and auditory signs (including dysacusia).
Volkmann contracture
 Contraction of forearm flexors because of compartment syndrome sequelae
Von Economo’s encephalitis
 Encephalitis lethargica, also associated with influenza A epidemic of 1918, associated with postencephalitic parkinsonism, first described in 1917
von Gierke’s disease
 Glycogen storage disease type I, deficiency in glucose-6-phosphatase, results in hepatomegaly and hypoglycemia
von Graefe sign
 In Grave’s disease, lag of the upper eyelid as it follows the rotation of the eyeball downward
von Hippel-Lindau disease
 Hemangioblastoma or cavernous hemangioma of the cerebellum, brain stem, or retina, adenomas, and cysts of the liver, kidney, pancreas, and other organs, 35% develop renal cell carcinoma, 3p
von Myenburg complexes
 Close to or within portal tracts, these are small clusters of modestly dilated bile ducts embedded in a fibrous, sometimes hyalinized stroma; these bile duct "microhamartomas" contain inspissated bile concrements and may communicate with the biliary tree; rather common and usually without clinical significance
von Recklinghausen’s disease
 Neurofibromatosis
von Recklinghausen’s disease of bone
 Generalized osteitis fibrosa cystica; hallmark of severe hyperparathyroidism, including increased bone cell activity, peritrabecular fibrosis, and cystic brown tumors
Von Willebrand factor
 vWF bridges collagen and platelets and favors platelet aggregation, ensuring platelet and vessel wall interactions; glycoprotein Ib-IX major receptor for vWF; vWF also serves as carrier for factor VIII; made in endothelial cells and megakaryocytes
Von Willebrand’s disease
 Deficiency in von Willebrand factor; frequency of 1%, most common inherited disorder of bleeding; type 1 and 3 reduced quantity of vWF; type 2 qualitative defects in vWF
von Zumbusch psoriasis
 Aka generalized acute pustular psoriasis

 

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From Andrew Yee, Harvard Med '00