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Laboratory Compendium |
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Lab | Normal | Comments |
Acetominophen | <200 ug/ml @ 4 hrs | Used to check for Tylenol overdose |
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Acetone | Negative in all dilutions | Ordered to help determine if patient in suspected DKA is experiencing lactic vs ketoacidosis. Note that negative screen does not rule out DKA (there are ketoacids that are not measured). |
AFB | No mycobacteria isolated | Used to check for mycobacteria - specify if order is for blood, urine, feces, respiratory/sputum, or miscellaneous (with or without smear) |
AFP | ?? | Alpha-Fetoprotein. Part of triple marker. Also used as a tumor marker for hepatocellular carcinoma, and is used as a screening test for Hep B and C patients. |
Albumin | 3.0-5.5 g/dl | (see LFT page) Usually used as a marker of hepatic synthetic capacity or as a nutrition marker |
Alcohol screen | None detected | Tests for ethanol, methanol, and isopropanol. Usually part of tox screening |
Aldosterone (serum) | 1.0-21.0 if >11 yo | (send-out to Mayo) Used in checking for HTN, renal function, adrenal function |
Alkaline Phosphatase | 38-126 u/L | (see LFT page) Used to check for hepatic damage. Also elevated in cholestasis, bone CA. |
ALA | 1.5-7.5 mg/24 if >6 yo | (send-out to Mayo) Aminolevulonic Acid. Urine test. A heme breakdown product that increases in porphyria. |
ALT (SGPT) | 15-75 u/L | (see LFT page) Elevated levels indicate hepatic damage |
Ammonia | 9-33 umol/L | Used in liver patients to help diagnose hepatic encephalopathy, which is seen in patients with cirrhosis or portal shunts. |
Amphetamine Screen | Negative Screen | Screen only. Confirmation sent out to Mayo. |
Amylase | 30-110 u/L | Elevated in pancreatic damage (sensitive but not specific marker for pancreatitis), pancreatic duct blockage |
Anaerobe Culture | No growth | Specify if order is for bone marrow, fluid, respiratory, tissue, or other. Use special collection tubes, deliver immediately. Reported when positive, negative is final at 48 hrs |
Anti-DNA | Negative | (send-out to Mayo) This test is a variant on the anti-nuclear antibody screens. Can order either single or double stranded - double is more specific for SLE. Can also send out for Quantitative if this is positive |
Anti-Gliaden Antibodies (IgG, IgA) | Varies with age and Ig | (Send-out to Mayo) Used to screen for gluten-sensitive enteropathy |
Anti Glomerular Basement Membrane Antibody | Negative | Two tests - one at FAHC, one at Mayo. Used to test for Goodpasture's or Anti GBM Disease. |
Anti Neutrophil Cytoplasmic Antibody (ANCA) | Negative | Elevated in the "pauci-immune vasculidities." C-ANCA associated with Wegener's P-ANCA associated with polyarteritis |
Anti Nuclear Antibody (ANA) | <40 dils | Elevated in lupus, other autoimmune coditions |
Antibody Screen | negative | aka "Coomb's Test (indirect). Used in working up hemolytic anemia. |
Arginine Vasopressin | ?? | (Send-out to Mayo) Used to check serum ADH (Vasopressin) levels, in SIADH or DI |
AST (SGOT) | 8-50 u/L | (see LFT page) Elevated levels indicate hepatic damage |
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Lab | Normal | Comments |
Bacterial Culture | No growth | Specify if order is for blood, bone marrow, feces (with or without smear), genital, object, respiratory/sputum, tissue, urine, or other. |
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Barbiturate Screen | Negative screen | Screen only. Confirmation sent out to Mayo. |
Basic Metabolic Panel (BMP) | see individual tests | see electrolytes and blood pages. Includes BUN, Calcium, Chloride, CO2, Creatinine, Glucose, Potassium, Sodium |
Benzodiazepine Screen | Negative screen | Screen only. Confirmation sent out to Mayo. |
Bilirubin | Unconj: 0.0-1.1 / Conj: 0.0-0.3 mg/dl | (see LFT page) Unconjugated increased with hepatic damage or increased heme breakdown. Conjugated increases with cholestasis or hepatocellular damage. Note that unconj + conj does NOT equal total - there are other fractions (delta, etc.) |
Bleeding Time | 3-10 minutes | Coag study. High operator variability. |
Blood Gas | see ABG | see ABG page. Helpful for analyzing respiratory, renal function; acid-base status. |
Blood Gas with Whole Blood Electrolytes | see individual tests | Includes pH, pCO2, pO2, Chloride, Potassium, Sodium |
BUN | 10-26 mg/dl | see electrolytes page. Decreased in malnutrition, liver disease. Increases in GI bleeds or any decreased GFR (such as renal failure), and in catabolic states. Ratio of BUN/Creat is often analyzed: if the ratio is >20:1, then volume depletion &/or hypoperfusion is probably present. |
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Lab | Normal | Comments |
C-Reactive Protein | < or = 1.0 mg/dl | Non-specific measure of inflammatory activity. |
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C. Dificile Toxin | Negative | Fecal study to detect C. diff (pseudomembranous) colitis, which is common in patients on ABX. |
C3 Complement | 79-152 mg/dl | Autoimmune response- will measure as decreased if reaction present, as complement is consumed. Measured as part of workup for renal failure - immune complexes will clog tubules. |
C4 Complement | 16-38 mg/dl | Autoimmune response- will measure as decreased if reaction present, as complement is consumed. Measured as part of workup for renal failure - immune complexes will clog tubules. |
CA 125 | <35 u/ml | Tumor marker for ovarian CA. |
Calcium | 8.5-10.5 mg/dl | Increased in malignancy, hyperparathyroid. Decreased in hypoalbuminemia, renal insufficiency, vit D deficiency. Can also order Ionized serum or Ionized whole blood, or urine Ca. |
Cannabinoid Screen | Negative screen | Screen only for marijuana products. Confirmation sent out to Mayo. |
Carbamezapine | 4-10 ug/ml | Carbamezapine = Tegretol, an anticonvulsant. Too much leads to lethargy, hepatic and renal damage. Too little does not control seizures. Reference range may not be accurate for specific patients. |
Carbon Dioxide (CO2) | 24-30 mEq | Proxy for bicarbonate - useful for assessing acid-base status. see ABG and electrolytes pages. |
Carboxyhemoglobin | <1.5% (non-smoker) 1.5-5.0% (smoker) | Used to test for CO (carbon monoxide) poisoning. Tends to be normally elevated in smokers. |
CBC | see individual tests | aka Hemagram. see blood page. Includes WBC, RBC, Hgb, Hct, MCV, MCH, MCHC, RDW, Platelets |
CD4 / CD8 | see individual tests | see HIV page. CD4 count is used as a marker in HIV progression. |
CEA | <3.0 ng/ml in non-smokers | A tumor marker that is used for monitoring recurrence in patients with known CEA-producing tumors. These can be any adenocarcinomas, although typically used for colon CA. Note that this is used for progression or recurrence - NOT as a screening tool, an application for which this test is not particularly useful. |
Chloride | 96-110 mEq/L | see electrolytes page. Increased in dehydration, CF, hyperparathyroid. Decreased in dilution, SIADH, DKA. |
Cholesterol | <200 mg/dl | Total chol - needs breakdown to be clinically useful (HDL, LDL, TG). 200-239 = Borderline. >240 = High Risk. |
CK-MB | 0-5 ng/ml | Used to rule out MI. Starts to rise 4-6 hours after a cardiac event, and peaks at 12-24 hours. Returns to normal by 1-3 days. Remains negative in patients with angina, even if high-risk and unstable - specific for infarction of cardiac muscle. Can be falsely elevated in skeletal muscle damage or with renal failure. |
CK-MB with Total CK | see individual tests | Using both values allows you to calculate the CK Index. The Index is calculated as CK-MB/Total CK. If the index is elevated, then the increase in CK-MB is probably due to cardiac damage, whereas if it's low (<1%), then the cause is probably skeletal muscle. |
Cocaine Metabolites | Negative screen | Screen only. Confirmation sent out to Mayo. |
Cold Agglutinins | Negative screen | Are a cause of normocytic anemia. |
Comprehensive Metabolic Panel (CMP) | see individual tests | Includes Albumin, Alk Phos, ALT, AST, Bili (conj & unconj), BUN, Calcium, Chloride, CO2, Creatinine, Glucose, Potassium, Sodium, Total Protein |
Coomb's - Direct | negative | aka "Direct Antiglobulin" - part of workup for hemolytic anemia. This test looks specifically for antibodies attached to RBC's, and will be positive in autoimmune hemolytic anemias (HA) and transfusion reactions, but negative in non-autoimmune HA. |
Coomb's - Indirect | negative | aka "Antibody Screen" - part of workup for hemolytic anemia. This test looks for RBC antibodies in serum. If a person has received a blood transfusion in the past and has developed antibodies to an RBC antigen, then this test will be positive. |
Cortisol | 7-9am: 4.3-22.4 ug/dl 3-5pm:3.1-16.7 ug/dl | Can help to diagnose Cushing's, Addison's. Dexamethasone, given at night, should suppres AM peak of cortisol - if it doesn't, susupect Cushing's ("Dexamethasone Suppression Test"). |
Creatinine | 0.7-1.5 mg/dl | see electrolytes page. Increases in renal insufficiency (decreased GFR). Decreases in states of increased GFR (such as pregnancy), decreased muscle mass/use. Ratio of BUN/Creat is often analyzed: if the ratio is >20:1, then volume depletion &/or hypoperfusion is probably present. |
Creatinine Clearance | Proxy measurement for GFR, | |
Cryoglobulins | Negative screen at 72 hours | see anemia page - same as cold agglutinin, which clogs vessels when <98o and thereby causes vasculitis. Seen in renal failure, and associated with liver disease (particularly Hep C), as well as being caused by mycoplasma and EBV. |
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Lab | Normal | Comments |
D-Dimer | <50 ug/ml | Fibrinogen breakdown product. Extremely non-specific acute phase reactant. Reliably elevated in PE, DVT, DIC. |
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Depakote | 50-100 ug/ml | aka Valproic Acid |
Dexamethasone Suppression Test | 50-100 ug/ml | Baseline level, then three post-test samples are drawn. Used to diagnose Cushing's - if 1o, dexamethasone will NOT suppress cortisol. |
Digoxin | 0.5-2.0 ng/ml | Dig levels need to be monitored to ensure therapeutic range, although values within reference range may not be therapeutic for individual patients. Dig toxicity can occur at any level and can be fatal. |
Dilantin | ?? | aka Phenytoin |
Direct Antiglobulin | Negative | aka Coomb's Test (direct) - used for working up hemolytic anemia. |
Drug Screen 6 | Negative Screen | Includes Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Cannabinoids, and Opiates. |
Drug Screen - Agitated | Negative Screen | Includes Cocaine and Amphetamines |
Drug Screen - Sedated | Negative Screen | Includes Barbiturates, Benzodiazepines, and Opiates |
Drug Screen - Comprehensive | Negative Screen | (send-out to Mayo) - takes 2-3 days. Can specify blood, urine, or both. |
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Lab | Normal | Comments |
Electrolytes | see individual tests | Includes Chloride, CO2, Potassium, Sodium |
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Electrophoresis, Hemoglobin | No abnormal hemoglobins identified | Useful for diagnosing hemoglobinopathies, such as thalassemias. |
Electrophoresis, Serum | Albumin: 49-61% Alpha 1: 2.4-4.9% Alpha 2: 10-19% Beta: 9-14% Gamma: 11-21% Total Protein: 6.0-8.5 g/dl | Individual bands are stronger in myeloma |
Erythropoeitin | 4-24 mU/mL | (send-out to Mayo) Created in kidneys, stimulates red blood cell production. Occasionally tested when other causes of anemia are ruled out. |
Estradiol | ?? | Elevated in polycystic ovarian disease, but not as useful a marker as the LH/FSH ratio. Used as part of a fertility workup to assess the menstrual cycle, and to time in vitro fertilization. Can be used to confirm menopause, but is not as good as FSH for this purpose. |
Ethanol, Blood | <10 mg/dl | Blood alcohol |
Ethylene Glycol | None detected | Antifreeze |
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Lab | Normal | Comments |
Factor __ Assay | 60-140% of normal | Assays available for Factors: 2, 5, 7, 8, 9, 10, 11, 12. Tested to rule out various specific hereditary coagulopathies. An antigen test is also available for Factor 8. |
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Factor V Leiden | Negative | (send-out to Mayo) Part of hypercoagulability workup. Factor V Leiden is a hereditary deficiency in the clotting cascade. |
Fecal Occult Blood | Negative | Non-specific, non-sensitive test for GI bleeding. |
Ferritin | see anemia page. Ferritin is storage form of iron. Low in iron-deficiency states, increased (particularly >70%) indicates hemochromatosis. Is also an acute phase reactant (meaning that it rises non-specifically in many inflammatory conditions). | |
Fetal Lung Maturity | >55 mg/g | <39 = immature 40-54 = borderline Blood, meconium and bilirubin (and other contaminants) may give false readings. |
Fibrinogen | 144-399 mg/dl | Increases in coagulopathies or any inflammatory process (it's an "acute phase reactant"). It drops in DIC. |
Folate | 2.8-18.0 ng/ml | see anemia page. Common cause of macrocytic anemia. Often low in alcoholics or with celiac sprue (and other intestinal conditions) |
Free Thyroxine Index | 1.3-4.1 | Includes T3 uptake, T4, and T7 calculation |
FSH | Part of amenorrhea workup, and a common test to confirm menopause. Also, used in conjunction with LH to diagnose POD (polycystic ovarian disease) - in this condition, the LH/FSH ratio is >2. | |
Fungus Culture | No fungus isolated/seen | Can order for Blood, Fluid, Genital, Nails, Oral, Respiratory/Sputum, Skin, Spinal Fluid, Tissue, Urine, or Other |
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Lab | Normal | Comments |
Gabapentin | 2.0-12.0 ug/ml | (send-out to Mayo) aka Neurontin. Loss of efficacy when serum concentrations below reference range. |
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GC Screen Culture | No Neisseria Gonorrhea isolated | Gonorrhea test - reported when positive, negative final at 48 hours. |
GGT | Gamma Glutyl Transerfase. see LFT page. A more specific LFT than AST or ALT - more directly indicates hepatic (as opposed to another source) damage. | |
Glucose 1 Hr Screen | <135 mg/dl | Gestational diabetes screen. If elevated, need to perform 3 hour tolerance test. |
Glucose 2 Hr Screen | <200 mg/dl | General diabetes screen. If elevated, meets criteria for DM. see diabetes page. |
Glucose 3 Hr Screen | ?? | Gestational diabetes screen. |
Glucose | ?? | see diabetes page for all diagnostic criteria - >200 on more than one occasion = diabetes. |
Glucose-6-Phosphate | 8.6-18.6 u/g of Hgb | If a patient has this deficiency, the use of sulfa (or some other) drugs can cause hemolytic crisis. |
Glucose, CSF | 60-80% of plasma glucose | Decreased with CSF bacteria (who eat sugar) |
Glucose, Serum or Plasma (Fasting) | <50yo: 70-115 mg/dl >50yo: 85-125 mg/dl | >125 needed on two occasions for diagnosis of DM. see diabetes page. |
Glucose, Urine | 0.003-0.025 g/dl | Rule of thumb is that blood glucose should be >250 before glucose spills into urine. |
GNRH | ?? | (send-out to Mayo) Gonadotropin Releasing Hormone. If pan-hypopituitary, this (and TSH and ACTH) will be decreased. |
Growth Hormone | (send-out to Mayo) Increased in acromegaly. Decreased in some short-stature conditions. |
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Lab | Normal | Comments |
Haloperidol | 5-16 ng/ml | aka Haldol. Low dose therapeutic = 2-5 ng/ml. High dose therapeutic = 10-40 ng/ml. Different ranges are therapeutic for individuals. Overdose can lead to extrapyramidal symptoms and tardive dyskinesia. |
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Ham's Test | No hemolysis | aka "sugar water test," used to diagnose paroxysmal nocturnal hemoglobinuria (a cause of anemia, which also leads to false positive urine dipsticks for blood). The test looks for fragile red blood cells, and has a reputation for not being reliable. |
Haptoglobin | 36-195 mg/dl | A test for intravascular hemolysis (seen in DIC, TTP, heart valve shearing). Haptoblogin binds to free hemoglobin, so it is consumed (and therefore decreases) in intravascular hemolysis, when lots of hemoglobin is freed. |
HCG | <4 mIU/ml | Human Chorionic Gonadotropin. Used as pregnancy test. If 4-10 mIU/ml, must repeat - not diagnostic. This is serum test - there is also a urine test, see Pregnancy test, urine |
HDL | >35 mg/dl | High-Density Lipoprotein. Must be taken fasting. Increases with exercise. |
Heavy Metal Panel | Arsenic: <0.07 ug/ml Cadmium: <5.0 ng/ml Lead, Adult: <20 ug/dl Lead, Peds: <10 ug/dl Mercury: <10 ng/ml | (send-out to Mayo) Test for Arsenic, Cadmium, Lead, Mercury. Not that toxic ranges include: Lead, Adult: >30 ug/dl Lead, Peds: >20 ug/dl Mercury: >50 ng/ml |
Hemagram | see individual tests | aka CBC. Includes WBC, RBC, Hgb, HCT, MCV, MCH, MCHC, RDW, and Platelets. see blood page for details |
Hemagram & Diff | see individual tests | Hemagram with 5-part differential (neutrophils, lymphocytes, basophils, monocytes, eosinophils). see blood page for details |
Hematocrit (HCT) | Decreased in blood loss, anemia. Increased in polycythemia, smokers. | |
Hemoglobin (Hgb) | Decreased in blood loss, anemia. Increased in hemoconcentration, polycythemia. | |
Hemoglobin A1C | <6% (non-diabetic) | Used to measure effectiveness of maintaining blood glucose over an extended period - the test is said to summarize glucose control over the 6 months prior to the blood draw. Glucose Control Index (for diabetics:) >= 10%: Poor 9-10%: Fair 8-9%: Good 7-8%: Excellent 6-7%: Near-Normal <=6%: Normal |
Heparin Platelet Antibody | Negative | Used to look for Heparin-induced, antibody-meidated platelet aggregation, seen in Heparin-induced thrombocytopenia (potentially fatal if untreated) |
Hep A Antibody | Negative | see hepatitis page. Positive indicates prior exposure - in which case the lab checks for IgM, which would indicate acute infection. |
Hep B | Negative | see hepatitis page. Surface antigen indicates acute infection, surface antibody indicates cleared infection. Core antibody indicates current or prior exposure. |
Hep C Antibody | Negative | see hepatitis page. 10% false positive, otherwise indicates prior infection with or without currently active viremia - confirm viremia with PCR. |
Hep C Genotype | variable | see hepatitis page. (send-out to Mayo) Used to distinguish between various strains of Hep C, which have different susceptibilities to various medications. |
Hep C RNA PCR | Negative | see hepatitis page. (send-out to Mayo) Used to confirm active Hep C. |
Hep D Antibody | Negative | see hepatitis page. (send-out to Mayo) Indicates current or prior exposure to Hep D. |
Herpes IgG Antibody | <=0.90 | Herpes test. Note that 0.91-1.09 is equivocal (non-diagnostic) - >1.10 is positive. |
Herpes Culture (HSV) | No herpes simplex recovered | Used for swab of vesicular fluid |
HIV Antibody | Non-reactive | see HIV page. HIV Test. If reactive, sent to Mayo for confirmation. Lab will not report results to patients - only to physicians. Sensitivity is currently >50 copies. Also, see viral load on this page |
HIV Confirmation | Negative | see HIV page. (send-out to Mayo) Used to confirm HIV. Done by Western blot, and positives are reported as either HIV1 or HIV2 positive. Actually a serotype (not a genotype, as often called), since it characterizes the antibody to HIV, not the HIV virus itself. |
HLA B27 | Detected or Not Detected | Increased in patients who are predisposed to seronegative spondylarthropathies, such as Reiter's, ankylosing spondylitis, Crohn's. Part of workup for patients with monoarticular arthridities. |
Homocysteine | 4.5-12.5 umol/L | Elevated in homocysteinuria, or other genetic defects. Recent studies show that an increase in homocysteine is correlated with an increased risk of cardiovascular disease. |
HPV | Negative | (send-out to Mayo) Human Papilloma Virus - predisposes to cervical CA. If positive, will determine which groups are present. |
HVA Urine | <8 mg/24 hrs (adult) | (send-out to Mayo) Homovanillic Acid - used to confirm pheochromocytoma, along with MVA |
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Lab | Normal | Comments |
Imipramine | 150-250 ng/ml | Therapeutic range, but different patients may respond to different levels |
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Immunodeficiency Panel | CD3: 67-84% CD4: 40-65% CD8: 10-38% Absolute CD4: 702-1791/ul | Can also be ordered with B and NK Cell markers: CD19: 7-22% CD16/56: 2-22% |
Immunofixation, serum | Negative | Looks for monoclonal immunoglobulins, as seen in myeloma |
Immunofixation, urine | Negative | Looks for monoclonal immunoglobulins, as seen in myeloma. Called Bence-Jones proteins when found in urine. |
Influenza | Negative | (send-out to state lab) Can order Influenza A Antibody, Influenza B Antibody, or Influenza B Vaccine Response. Can also order Influenza Culture. |
INR | 0.8-1.2 | International Normalized Ratio. Standardized lab used in place of PT to follow Warfarin (Coumadin) effectiveness. |
Insulin | Fasting: 0-22 ug/ml | Can be used to check for insulinoma (pancreatic cell tumor) |
Insulin Antibodies | <3% | Can be used to confirm this specific variant of DM2 |
Iron | see anemia page. Decreased in iron-deficiency anemia or anemia of chronic disease. | |
Iron Binding Capacity (IBC or TIBC) | 250-450 ug/dl | see anemia page. Decreases in malnutrition, anemia of chronic disease or iron deficiency, or hemochromatosis. |
Iron Saturation | 0.2-0.55 | A calculated value from Iron and IBC. Iron sat = Iron/IBC. Saturation >50% with Saturation normal with Saturation |
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Lab | Normal | Comments |
Kidney Stone Analysis | report | If not calcium-carbonate, unlikely to show up on x-ray. |
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Lactose Tolerance | ?? | Used to confirm suspected lactose intolerance. |
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LDH | 313-618 u/L | Lactose dehydrogenase Non-specific. Rises in hemolysis and PCP (penumonia). |
LDL | <130 mg/dl | see lipids page. Low-Density Lipoprotein. This value is generally calculated on the lipid panel - the only reason to order this test is if TG are high (>400), making calculation innacurate (and direct measurement needed). 130-160 = Borderline. >160 = High Risk. |
Lead | Child: 0-9 ug/dl Adult: 0-20 ug/dl | also part of Heavy Metal Screen |
Leukemia Panel | report | Can be ordered for Bone Marrow or Peripheral Blood |
LH | Used as part of workup for amennorrhea / oligomennorrhea, or as test for menopause or ovarian failure. Also, used in conjunction with FSH to diagnose POD (polycystic ovarian disease) - in this condition, the LH/FSH ratio is >2. | |
Lipase | 0-210 u/L | Elevated in pancreatic damage (sensitive but not specific marker for pancreatitis), pancreatic duct blockage |
Lipid Panel | see individual tests | see lipids page. Should be fasting x 8 hours. Includes Cholesterol, Triglycerides, HDL, LDL (LDL is calculated using the formula LDL = total chol - HDL - TG/5), and Chol/LDL ratio. |
Lithium | 0.6-1.2 mmol/L | Therapeutic range. Toxic = >2.5 mmol/L, although toxicity can occur at any level. |
Liver Panel (LFT) | see individual tests | Includes Albumin, Alk Phos, ALT, AST, Bili-Conj, Bili-Unconj, Bili-Total, and Total Protein. see LFT page. |
Lupus Anticoagulant Workup | see individual tests | Includes PTT, 50/50 Mix, Dilute Russell Viper Venom Time. Will confirm if positive. |
Lyme Antibody | Negative | A screening test - cannot distinguish between IgG and IgM, although it will detect both. Confirm with Lyme Antibody by Western Blot (a send-out to Mayo). |
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Lab | Normal | Comments |
Magnesium | 1.4-2.3 mEq/L | Decreased in malnutrition. Should check mag when K+ or Ca+ are decreased - they often coincide. Low mag leads to tetany. Elevated in renal failure. Bartlett's can lead to increased mag loss by kidneys. |
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Methanol | Negative | Part of Alcohol Screen |
Methemoglobin | 0.004-0.015 | A breakdown product of hemoglobin. Increased in CO poisoning. Biochemically, methemoglobin has had its iron changed from ferrous (2+) to ferric (3+) by oxidation - this is caused by a variety of chemicals, including primaquin, sulfonamides, Dapsone, and others. |
Microalbumin | <1.9 mg/dl Microalbumin <20 mg/g Creatinine | Urine test. Increases in renal failure. |
Monoclonal Protein, Quantitative | interpretation | Urine test - a follow-up to positive electophoresis indicating myeloma |
Monospot | Negative | Blood test for mononucleosis |
Myoglobin | 0.00-0.09 ug/ml | (send-out to Mayo) A urine test. Increased in rhabdomyolysis (muscle breakdown). Buildup in kidneys can cause renal failure (ATN). |
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Lab | Normal | Comments |
Newborn Screen | see individual tests | (send-out to state lab) Includes PKU, T4, Galactose screen. |
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Niacin | ?? | (send-out to Mayo) Decrease leads to dermatitis, diarrhea, dementia. Seen in alcoholics |
Nortriptyline | 50-150 ng/ml | Tricyclic antidepressant. Can use to check for therapeutic range or overdose |
Opiate Screen | Negative screen | Screen only. Confirmation send out to Mayo. |
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Osmolality | Can also order for CSF, but no reference range. Use to check for hemoconcentration / hemodilution, and for concentration of urine (particularly in working up suspected SIADH/DI) | |
Osmotic Fragility | Hemolysis less than or equal to control | Used to help diagnose paroxysmal nocturnal hemoglobinuria (PNH). |
Oxygen Saturation (O2 Sat) | 0.95-0.99 | Arterial sample. Decreased in V/Q problems, multiple pulmonary or cardiac causes. |
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Lab | Normal | Comments |
Parathyroid Hormone | 10-65 pg/dl | Reference range assumes normal calcium. The hormone leads to increased absorption and release of Ca into the bloodstream (at the expense of bone) |
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pH | 7.38-7.42 | See ABG page. Low means acidosis, high means alkalosis. |
Phenobarbital | 15-40 ug/ml | Barbiturate used as anticonvulsant. Too low leads to seizures, too high leads to respiratory depression, hepatic dysfunction, megaloblastic anemia |
Phenylalanine | 0.4-3.7 mg/dl | Newborn screen used to test for an inborn error of metabolism - PKU, or phenylketonuria. Borderline: 3.8-10.0 mg/dl Elevated: >10.0 mg/dl |
Phenytoin | 10.0-20.0 ug/ml | aka Dilantin, an anticonvulsant. High levels can lead to arrythmia, multi-organ damage |
Phosphorous | 2.5-4.5 mg/dl | Decreased in malnutrition. Tends to trend with Mag and Ca+. Decreased in PKA, refeeding syndrome (both K+ and phos will be decreased). Decreased phos leads to hemolytic anemia and heart failure. Elevated in renal failure - can cause calciphylaxis (CaPO4 deposits throughout the body). |
Platelet Aggregation | See path report | Ordered when unexplained coagulopathy present |
Porphobilinogen Screen | Negative screen | Increased in porphyrias. |
Porphyrins | many individual tests | (send out to Mayo) Used when porphyria screen positive for further analysis. Includes Uroporphyrins, Heptacarboxylporphyrins, Hexacarboxylporphyrins, Pentacarboxlporphyrins, Coproporphyrins, Porphobilinogen |
Porphyrin Screen | Negative screen | Used when porphyria suspected - if positive, order porphyrins. |
Potassium (K) | 3.5-5.0 mEq/L | see electrolytes page. Decreased in dilution, alkalosis, diuretic use. Increased in acidemia, renal insufficiency |
Prealbumin | 18-38 mg/dl | Nutrition lab - low prealbumin indicates poor nutritional status |
Preformed Antibody Screen | >5% | Looks for specific antibodies, the presence of which you've determined with an indirect Coomb's test. For example, the if the anti-D preformed antibody test is positive, the patient has an antibody to the D antigen on RBCs, so must get only Rh- blood. |
Pregnancy Test | Negative or Positive | Looks for elevated HCG. This test is equivalent to home pregnancy test. Serum test is more sensitive |
Profile Arthritis | see individual tests | Includes ANA and Rheumatoid Factor |
Profile Hepatitis A/B/C | see individual tests | Includes Hep A Antibody, Hep B Surface Ab and Ag, Hep B Core Ab, Hep C Ab. |
Profile Hepatitis B | see individual tests | Includes Surface Ab, Surface Ag, Core Ab |
Profile Prenatal | see individual tests | Includes Antibody Screen, ABO/Rh, Hep B Surface Ag, Syphilis Serology, Rubella IgG Ab, Hemagram. Can also be ordered without Rubella |
Profile Thyroid | see individual tests | Includes Free T4 and TSH |
Progesterone | see next column | |
Prolactin | see next column | |
Prostate Specific Antigen (PSA) | <50yo: 0-2.5 ng/ml 50-59yo: 0-3.5 ng/ml 60-69yo: 0-4.5 ng/ml >70yo: 0-6.5 ng/ml | Screening test for prostate CA. Confirm with biopsy |
Protein | 6.0-8.5 g/dl | Low in malnutrition or protein wasting states (enteropathy or nephropathy, for example). Can be followed daily - any decrease of ~1 g/dl is considered dramatic and evidence of protein wasting, as seen in exudative diarrhea. Protein elevated in gammopathies. Protein:Albumin ratio is increased in myeloma, autoimmune hepatitis. |
Protein, CSF | 15-60 mg/dl | Elevated when any organism in CSF, or when leaky BBB. Also, if CSF protein is elevated but no CSF bugs are grown, consider Guillian-Barre syndrome. |
Protein, Urine | <150 mg/24 hr | Increased in renal failure |
Prothrombin Time (PT) | 12.3-13.9 seconds | INR is more widely used indicator. Affected by Warfarin (Coumadin) |
Prothrombin Time 50/50 Mix | Requires interpretation | Mix is used when the question remains whether the coagulopathy is caused by a deficiency of a clotting factor or an antibody to that factor. The patient's blood is mixed with normal - if the problem is deficiency, the mixture will correct the coagulopathy - if it is an antibody, the coagulopathy will remain. |
PTT | 21-30 seconds | Affected by Heparin |
PTT 50/50 Mix | Requires interpretation | Mix is used when the question remains whether the coagulopathy is caused by a deficiency of a clotting factor or an antibody to that factor. The patient's blood is mixed with normal - if the problem is deficiency, the mixture will correct the coagulopathy - if it is an antibody, the coagulopathy will remain. |
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Lab | Normal | Comments |
Rabies Antibody | ?? | (send-out to Mayo) Rabies test |
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Renal Transplant Panel | CD3: 67-84% | ?? |
Renin | 0.5-2.5 ng/ml/hr | Part of a workup for renal vascular disease - if renal artery stenosis, would be increased. Not used by itself - also get aldosterone level |
Reticulocyte Count | 0.01-0.029 | +/- 100% inter-operator variability! Increased whenever increased red cell production. |
Rheumatoid Factor | <20 IU/ml | Elevated in rheumatoid arthritis |
RPR | see Syphilis serology. This is the newer syphilis test, more sensitive with fewer false positives. |
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Lab | Normal | Comments |
Salicylate | Negative: <2 mg/dl Therapeutic: <20 mg/dl | Toxic: >30 mg/dl Lethal: >60 mg/dl |
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Sed. Rate | Non-specific indicator for inflammation | |
Sickle Cell | Negative | Fairly definitive test for sickle-cell disease |
Sjogren's Antibodies | Negative | Test for Sjogren's, an autoimmune disease with anti-SS DNA antibodies |
Sodium | 136-145 mEq/L | see electrolytes page. Decreased in hemodilution, SIADH, renal failure. Increased in vomiting, diarrhea, DI. |
Sperm Antibody | <20% | Percentage of sperm bound to antibody must be weighed against total sperm count for meaningful interpretation. Test is used in cases of difficulty conceiving. |
Sputum Cytology | varies | Three consecutive morning samples should be ordered. |
Strep Screen | None isolated | Can be ordered for Group A or Group B. Reported when positive, negative is final at 48 hours. |
Sweat Test | Chloride: <30 mEq/L Sodium: <60 mEq/L | Used to diagnose cystic fibrosis - one of the findings in CF is elevated Cl- production. Equivocal: 40-60 mEq/L Abnormal: >60 mEq/L |
Spyhilis Serology | Negative | RPR or VRDL ?? |
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Lab | Normal | Comments |
T3 Uptake | 28-36% | An indirect measure of thyroid-binding globulin. T3 Uptake, when multiplied by total T4, is equivalent to the "free thyroxine index," or FTI. The FTI is also known as T7, or a "calculated free T4." |
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T3, Free | 2.3-4.2 pg/ml | (send-out to Mayo) see thyroid page. Elevated in hyperthyroid, decreased in hypothyroid. The free test is more accurate than the total, as it is not affected by changes in binding proteins. |
T3, Total | 60-181 ng/dl | see thyroid page. Elevated in hyperthyroid, decreased in hypothyroid |
T4 | 4.5-10.9 ug/dl | see thyroid page. Elevated in hyperthyroid, decreased in hypothyroid |
T4, Free | 0.8-1.8 ng/dl | see thyroid page. Elevated in hyperthyroid, decreased in hypothyroid. The free test is more accurate than the total, as it is not affected by changes in binding proteins. |
Testosterone | Tested in multiple conditions, including prostate conditions, sperm production problems, female hirsutism, suspected androgen-insensitivity, etc. Can send-out to Mayo for Total & Free studies | |
Thiamine (B1) | ?? | (send-out to Mayo) Deficiency is common in alcoholics, and leads to Wernicke's Encephalopathy &/or Korsakoff's Dementia. Giving glucose without giving thiamine can cause Wernicke's - always give thiamine with glucose |
Thyroid Cascade | see individual tests | see thyroid page for complete algorithm. (TSH +/- => Free T4 +/- => Total T3) |
TORCH Screen | see individual tests | Includes Toxoplasmosis IgG Ab, Rubella IgG Ab, CMV, Herpes. Commonly transmitted diseases during childbirth |
Transferrin | 202-336 mg/dl | see anemia page. Transporter for iron in serum. Increases during iron deficiency |
TRH Stimulation | report | TSH levels are drawn at baseline, 30, and 60 minutes after admin of TRH. Can help to distinguish between secondary (pituitary) and tertiary (hypotahalamic) causes of thyroid dysfunction |
Tricyclic Screen | :<500 ng/ml | Potentially toxic > 500, although different levels are appropriate for different patients. Helpful in assessing possible OD |
Triglyceride | 35-160 mg/dl | see lipids page. Part of lipid profile. >1000 can cause pancreatitis. High TG is an independent (although not widely cited) risk factor for CAD. Hypertriglyceridemia is often familial, and is also often seen in insulin resistance. |
Triple Markers | report | Includes AFP, HCG, and Unconjugated Estriol |
Troponin I | <0.15 ng/ml | Used to help rule out MI, along with CK-MB. Troponin I rises 4-8 hours after an event, peaks 12-24 hours after the event, and stays elevated for 7-10 days, as compared to CK-MB, which only stays elevated for 1-3 days. Troponin I is specific for cardiac damage, but not for MI - it is useful as a marker of generalized myocardial injury, including high-risk unstable angina. Indeterminate: 0.15-1.50 ng/ml Positive: >1.50 ng/dl |
TSH | 0.35-5.50 uIU/ml | see thyroid page. Elevated in primary hypothyroid, decreased in primary hyperthyroid. Elevated in secondary hyperthyroid, decreased in secondary hypothyroid |
Tzank Smear | Negative | Herpes test |
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Lab | Normal | Comments |
Uric Acid (Urate) | Elevated in renal insufficiency &/or gout. | |
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Urinalysis | see individual tests | see urinalysis page |
Urine Cytology | report | Be certain to include any history of CA, radiation, chemo in order |
Valproic Acid | 50-100 ug/dl | aka Depakote, for seizure disorder or bipolar disorder. OD can lead to hepatic failure, bone marrow suppression |
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VDRL | ?? | see Syphilis Serology. Can send CSF to state lab. This test has been replaced by RPR (which is more sensitive and specific for syphilis), but is still available by specific request. |
Viral Load | negative | see HIV page. An HIV test, done by PCR. Used to follow the progress of therapy and to help plan for prophylaxis. Also is used to diagnose HIV seroconversion syndrome - the mono-like syndrome that occurs during first exposure to HIV. When first infected, patients' HIV screens will be negative, but viral load will be positive. |
Vitamin __ | varies | Can order Vitamins A, B1, B6, B12, C, D,125-Dihydroxy, D,25-Hydroxy, E, K1 |
VMA | 2-10 mg/24 hrs | Vanillylmandelic acid - 24 hour urine test used to diagnose pheochromocytoma, along with HVA |
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Lab | Normal | Comments |
WBC | 3.2-9.8 | see blood page. Increased in infection, inflammation, leukemias. Decreased in autoimmune disease, bone marrow dysfunction. |
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Zinc | 0.66-1.10 ug/ml | Elevated zinc most likely from over ingestion, can cause copper deficiency &/or leukopenia. |
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